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The authors have examined the gastric content of 162 patients with duodenal ulcer, 155 with chronic atrophic gastritis and 101 healthy subjects. In all groups under observation there were isolated Helicobacter pylori strains. In healthy subjects and in patients with duodenal ulcer with no H. pylori, a negative correlation between the amount of H. pylori and pH, number of bacteria, volume of gastric content and gastrin concentration in gastric juice has been observed. In patients with atrophic gastritis and duodenal ulcer in the presence of H. pylori, a positive correlation between the density of microbes and the concentration of gastrin and a negative correlation between the number of bacteria and pH, volume of gastric content and the concentration of gastrin have been observed. The use of the new microbiological method may help in the early diagnosis of patients with duodenal ulcer and atrophic gastritis with H. pylori.Regulatory, structural and functional aspects of glycogen metabolism in rat adipose tissue.
We have tested the hypothesis that the generation of glycogen in rat adipose tissue is regulated both by glycogen synthetase and by the post-phosphorylating enzyme glycogen phosphorylase a. The latter has been studied using the actions of glucagon and cAMP and by relating the insulin-sensitive response to its ability to stimulate this enzyme. It is concluded that intracellular glycogen regulation in rat adipose tissue is more complex than previously suggested. something to do
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